The Prophet ﷺ was taught wording for exactly this — for worry that will not lift, for grief, for the night when the mind will not stop. These are not a replacement for treatment or for talking to someone; they are what to say while you carry it.
When worry and sadness will not lift
اللّٰهُمَّ إِنِّي أَعُوذُ بِكَ مِنَ الْهَمِّ وَالْحَزَنِ، وَالْعَجْزِ وَالْكَسَلِ، وَالْبُخْلِ وَالْجُبْنِ، وَضَلَعِ الدَّيْنِ وَغَلَبَةِ الرِّجَالِ
Allāhumma innī aʿūdhu bika minal-hammi wal-ḥazan, wal-ʿajzi wal-kasal, wal-bukhli wal-jubn, wa ḍalaʿid-dayni wa ghalabatir-rijāl
O Allah, I take shelter with You from worry and grief, from being unable and being lazy, from stinginess and cowardice, from being crushed by debt and overpowered by people.
Anytime the weight will not shift; the Prophet ﷺ said it often. · Ṣaḥīḥ al-Bukhārī 6369
When something serious has happened
لَا إِلٰهَ إِلَّا اللّٰهُ الْعَظِيمُ الْحَلِيمُ، لَا إِلٰهَ إِلَّا اللّٰهُ رَبُّ الْعَرْشِ الْعَظِيمِ، لَا إِلٰهَ إِلَّا اللّٰهُ رَبُّ السَّمٰوَاتِ وَرَبُّ الْأَرْضِ وَرَبُّ الْعَرْشِ الْكَرِيمِ
Lā ilāha illa-llāhul-ʿAẓīmul-Ḥalīm, lā ilāha illa-llāhu Rabbul-ʿArshil-ʿAẓīm, lā ilāha illa-llāhu Rabbus-samāwāti wa Rabbul-arḍi wa Rabbul-ʿArshil-Karīm
There is no god but Allah, the Most Great, the Most Forbearing. There is no god but Allah, Lord of the Mighty Throne. There is no god but Allah, Lord of the heavens, Lord of the earth, Lord of the Noble Throne.
At a moment of real distress — the Prophet ﷺ said this one at such times. · Ṣaḥīḥ al-Bukhārī 6346; Ṣaḥīḥ Muslim 2730
The call of Yūnus عليه السلام, from inside the dark
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Lā ilāha illā anta subḥānaka innī kuntu minaẓ-ẓālimīn
There is no god but You. Glory be to You. I have been one of the wrongdoers. He was answered from three layers of darkness, and this is the wording the Qur'an records.
When you feel you brought the trouble on yourself and see no way out. · Qur'an 21:87
When people are against you
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Ḥasbunā-llāhu wa niʿmal-wakīl
Allah is enough for us, and the best One to depend on. This is what the believers said when they were warned that armies had gathered against them.
When you are outnumbered, threatened or afraid of what people will do. · Qur'an 3:173
Calling on Him by the two names of life
يَا حَيُّ يَا قَيُّومُ بِرَحْمَتِكَ أَسْتَغِيثُ
Yā Ḥayyu yā Qayyūm, bi-raḥmatika astaghīth
O Ever-Living, O Sustainer of all, by Your mercy I call for help. Al-Ḥayy is the One whose life never ends; al-Qayyūm is the One holding everything else up.
When trouble presses on you. · Sunan at-Tirmidhī 3524
Say them as often as you need to. Several were said by the Prophet ﷺ repeatedly rather than once, and one of them — the du'ā of Yūnus عليه السلام — was said from inside real distress.
Every du'ā above can be heard aloud. Where the words are Qur'an, the Arabic comes from the Quran.com API and is shown exactly as served, with a link into the muṣḥaf.